Professor of Computational Physiology, Department of Computer Science, University of Sheffield - 2014 to present. Moved to Sheffield in January 2003 as Senior Lecturer in the Department of Computer Science. Promoted to Reader in Computer Science in 2008, and awarded personal chair in 2014.
British Heart Foundation Lecturer, School of Biomedical Sciences,
University of Leeds - 1998 to 2003
Joined Computational Biology Laboratory as independent Fellow to pursue
interest in ventricular fibrillation using computational models. Developed
new model of ventricular fibrillation in the whole heart coupled to a torso
geometry. Studied tissue effects of gene mutations affecting specific ion
channels in the heart. As well as academic publications, this work has
featured in Scientific Computing World (Oct/Nov 2000), The Guardian (31-may-2001),
and BBC News Online (23-jan-2002). Appointed an Honorary Research Clinical
Scientist at the Leeds Teaching Hospitals NHS Trust.
Senior Research Physicist, Freeman Hospital, Newcastle upon Tyne
- 1996 to 1998
Nonlinear analysis of intracardiac and body surface ECG signals during
human ventricular fibrillation confirmed periods of order exist. Lead interdisciplinary
group of clinicians, scientists and nurses in studies of heart rate and
blood pressure variability in the elderly, heart transplant recipients,
and drug trials.
British Heart Foundation Intermediate Research Fellow, Freeman Hospital,
Newcastle upon Tyne - 1993 to 1996
Challenged prevailing view of electrical anarchy during ventricular
fibrillation by discovery of unexpected coherence between multi-lead electrocardiograms.
Developed software for analysis and modelling of heart rate and blood pressure
variability. British
Heart Foundation Junior Research Fellow, Freeman Hospital, Newcastle
upon Tyne - 1991 to 1993
Joined interdisciplinary team of physicists and clinicians investigating
mechanisms of ventricular fibrillation. Identified new features in the
electrocardiogram of ventricular fibrillation using objective criteria
from signal processing. Documented incidence of self-terminating ventricular
fibrillation, results published in the Lancet.
Research physicist, Freeman Hospital, Newcastle upon Tyne - 1989
to 1991
Developed instrumentation and software to detect and record episodes
of cardiac arrhythmia from patients. Evaluated commercial arrhythmia detection
algorithms, and implemented a new algorithm based on an artificial neural
network.
PhD Student, Freeman Hospital and University of Newcastle upon Tyne
- 1986 to 1989
Developed instrumentation and software to acquire blood-gas and perfusion
data from oxygenators (artificial lungs) during over 200 clinical cardiopulmonary
bypass procedures for open heart surgery. Used these data to compare the
controllability and gas transfer efficiency of different designs of oxygentor.
Member of the IEEE Engineering and Biology Society
Corporate member of the Institute of Physics and Engineering and Medicine
State Registered Clinical Scientist.